CD49f-PE, human and mouse 30 tests
货号：
130-100-096 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-096 |
| 描述 | Clone GoH3 reacts with CD49f, a 120 kDa transmembrane glycoprotein also known as α6 integrin. Integrins are integral cell-surface proteins composed of an α chain and a β chain and are involved in cell adhesion as well as cell-surface mediated signaling. CD49f associates with integrin β1 chain (CD29) to form VLA-6 and with integrin β4 chain (CD104) to form the α6 β4 complex, which plays a critical structural role in the hemidesmosome and constitutes a receptor for laminin in epithelial cells. CD49f is furthermore expressed on T cells, monocytes, platelets, endothelial cells, trophoblasts of placenta, and spermatogonial stem cells. Clone GoH3 antibody has been reported to block laminin binding in vitro and to block integrin α6 function in vivo. |
| 别名 | ITGA6, α6 integrin, ITGA6B, VLA-6, CD49f, VLA-6α |
| 克隆号 | GoH3 |
| 同种亚型 | rat IgG2aκ |
