Anti-KI-67-PE, human&mouse 30 tests
货号：
130-100-290 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-290 |
| 描述 | Clone REA183 recognizes Ki-67 antigen, a nuclear and nucleolar protein, which is strictly associated with cell proliferation. Two Ki-67 isoforms with molecular weight, 395 and 345 kDa are known. Both isoforms contain 16 “Ki-67 repeat“ sequences, each of which includes a conserved 66 bp “Ki-67 motif“. Expression of Ki-67 protein is present during all active phases of the cell cycle (G(1), S, G(2), and mitosis), but is absent from resting cells (G(0)). Due to strict association of Ki-67 with proliferating cells, Ki-67 is often used as an indicator of the “growth fraction“ of a given cell population. The N-terminal portion of Ki-67 contains a forkhead associated (FHA)1 domain, which is involved in interaction with proteins such as Hklp2 and NIFK. Additional information: Clone REA183 displays negligible binding to Fc receptors. |
| 别名 | MKI67, KIA, MIB-, MIB-1, PPP1R105, Ki67 |
| 克隆号 | REA183 |
| 同种亚型 | recombinant human IgG1 |
