Ms CD107b IHC Pure M3/84 1mL
货号：
550292 基本售价：
3192.0 元 规格：
1mL
产品信息
概述| 货号 | 550292 |
| 描述 | The M3/84 monoclonal antibody specifically binds to CD107b which is also known as Mac-3, Lysosome-associated membrane protein 2 (LAMP-2/Lamp2/Lamp II), and Lysosomal membrane glycoprotein type B (LGP-B). CD107b is a single-pass type I transmembrane glycoprotein that constitutes a major integral membrane protein of lysosomes and may play a role in lysosomal function. CD107b is also expressed on the surface of mouse mononuclear phagocytes. Surface expression of the 92-110-kDa glycoprotein antigen increases during differentiation of monocytes to activated macrophages and may play a role in adhesion. The M3/84 mAb can detect CD107b antigen on tissue macrophages, thioglycollate-elicited peritoneal macrophages, and some myeloid cell lines, but not on lymphocytes or monocytes. In the bone marrow, very few cells display CD107b antigen on the surface, but a large proportion express cytoplasmic CD107b. The M3/84 antibody has also been reported to stain dendritic cells and endothelium in sections of thymus (both medulla and cortex), lymph nodes, spleen (white pulp), and gut-associated lymphoid tissue. |
| 别名 | CD107b; Lamp2; LAMP-2; Lysosome-associated membrane glycoprotein 2; LGP-B |
| 同种亚型 | IgG1,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | IHC(F), IHC(Fr) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse C57Bl/6 peritoneal exudate cells |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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| 存储溶液 | Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide. |
| 浓度 | 31.25 µg/ml |
