Human Interleukin-17A/F Heterodimer (hIL-17A/F)
货号：
8846SC 基本售价：
2734.0 元 规格：
10ug
产品信息
性能| 供应商 | CST |
| 背景 | IL-17A/F is a cystine-linked heterodimer of IL-17A and IL-17F (1,2). IL-17A/F is produced by Th17 cells, and γδ T cells (1,2). IL-17A/F stimulates the production of pro-inflammatory cytokines and neutrophil chemoattractants, thereby functioning as a bridge between adaptive and innate immunity (1-3). Some research studies suggest that IL-17A/F may be involved in mucosal immunity against some bacterial infections and has a putative role in some autoimmune disorders (3,4). The receptor for IL-17A/F consists of a heterodimer of IL-17RA and IL-17RC and signaling through this receptor leads to the activation of the Erk1/2 and NF-κB pathways (1). |
| 存放说明 | 4C |
| 纯度 | >98% as determined by SDS-PAGE of 6 μg reduced (+) and non-reduced (-) recombinant hIL-17A/F. All lots are greater than 98% pure. |
参考图片The purity of recombinant hIL-17A/F was determined by SDS-PAGE of 6 µg reduced (+) and non-reduced (-) recombinant hIL-17A/F and staining overnight with Coomassie Blue.重组蛋白hIL-17A/F的纯度用6 µg 降解(+)和未降解(-)的蛋白走SDS-PAGE 胶来观察。考马斯亮蓝染色过夜。 |
The production of IL-6 by 3T3 MEFs WT cultured with increasing concentrations of hIL-17A/F was assessed. Media from cells incubated with hIL-17A/F for 24 hours was collected and assayed for IL-6 by ELISA and the OD450 was determined.用逐渐递增浓度的hIL-17A/F诱导3T3 MEFs WT细胞产生IL-6实验。细胞在hIL-17A/F中培养24小时后取培养基，通过ELISA和OD450来确定IL-6的量。 |
