| 货号 | 1097/10 |
| 别名 | [2aR-[2aα,4β,4aβ,6α,9α(αR*,βS*),11α,12α,12aα, |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Antitumor agent; promotes and stabilizes tubulin polymerization, causing cell cycle arrest. Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 853.92 |
| 分子式 | C47H51NO14 |
| 可溶性/溶解性 | Soluble to 25 mM in ethanol and to 100 mM in DMSO with gentle warming |
| 参考文献 | Parket al (2004) Taxol induces caspase-10-dependent apoptosis. J.Biol.Chem. 279 51057. PMID: 15452117. Raoet al (1999) Characterization of the taxol binding site on the microtubule. J.Biol.Chem. 274 37990. PMID: 10608867. Rowinskyet al (1990) Taxol: a novel investigational antimicrotubule agent. J.Natl.Cancer Inst. 82 1247. PMID: 1973737. McGuireet al (1989) Taxol: a unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms. Ann.Intern.Med. 111 273. PMID: 2569287. Merck Index 127117. |