| 货号 | 0768/25 |
| 别名 | 2-Amino-6-trifluoromethoxybenzothia |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Psychotropic agent with anticonvulsant, hypnotic, anxiolytic, anti-ischemic and anesthetic properties. Inhibits glutamate release from presynaptic terminals and increases Na+-dependent glutamate uptake in rat cortical synaptosomes. Blocks voltage-dependent Na+ channels and inhibits GABA uptake by striatal synaptosomes; neuroprotective. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 270.66 |
| 分子式 | C8H5F3N2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in water with gentle warming |
| 参考文献 | Fumagalliet al (2008) Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1. Eur.J.Pharmacol. 578 171. PMID: 18036519. Songet al (1997) Differential action of riluzole on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels. J.Pharmacol.Exp.Ther. 282 707. PMID: 9262334. Taylor and Meldrum (1995) Na+ channels as targets for neuroprotective drugs. TiPS 16 309. PMID: 7482996. Umeniya and Berger (1995) Inhibition by riluzole of glycinergic postsynaptic currents in rat hypoglossal motoneurones. Br.J.Pharmacol. 116 3227. PMID: 8719800. |