| 货号 | 0994/100 |
| 别名 | 1-(1H-Indol-4-yloxy)-3-[(1-methylet |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | 5-HT1A/1B receptor antagonist, with roughly equal affinity for each subtype. A partial agonist at mouse and human β3-adrenoceptors. (S)-(-)-Pindolol (Cat. No. 1060) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 248.32 |
| 分子式 | C14H20N2O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Cliffordet al (1998) Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT1Aautoreceptorin vivo. Br.J.Pharmacol. 124 206. PMID: 9630361. Corradettiet al (1998) Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT1A receptors in the rat brain. Br.J.Pharmacol. 123 449. PMID: 9504386. Hoyeret al (1994) VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 46 157. PMID: 7938165. Blinet al (1993) Structural and conformational features determining selective signal transduction in the β3-adrenergic receptor. Mol.Pharmacol. 44 1094. PMID: 7903415. Merck Index 127597. |