| 货号 | 4914/100U |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Potent blocker of voltage-gated sodium channels (IC50 values are 0.6, 42, and 72 nM for NaV1.2, NaV1.3 and NaV1.5 respectively). Blocks inward sodium currents in a voltage-dependent manner. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4059.74 |
| 分子式 | C176H269N51O |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | DCLGFLWKCNPSNDKCCRPNLVCSRKDKWC (Modifications: Disulfide bridges: 2-17,9-23,16-30) |
| 参考文献 | Onoet al (2011) Characterization of voltage-dependent calcium channel blocking peptides from the venom of the tarantula Grammostola rosea. Toxicon. 58 265. PMID: 21740921. Bosmanset al (2006) Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes. Mol.Pharmacol. 69 419. PMID: 16267209. |