| 货号 | 2770/10 |
| 别名 | (S)-N-[7-[(4-Aminobutyl)amino]hepty |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | AMPA receptor antagonist. Non-selective homomeric GluR3 and GluR1 receptor antagonist (IC50 values are 263 and 296 nM respectively). Inhibits homomeric GluR3 and GluR1 with a 100-fold greater potency than heteromeric GluR1/2 and GluR2/3 receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 507.54 |
| 分子式 | C24H42N4O3 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Poulsenet al (2013) Evaluation of PhTX-74 as subtype-selective inhibitor of GluA2-containing AMPA receptors. Mol.Pharmacol. 85 261. PMID: 24220009. Nilsen and England (2007) A subtype-selective, use-dependent inhibitor of native AMPA receptors. J.Am.Chem.Soc. 129 4902. PMID: 17391037. |