| 货号 | 4137/50 |
| 别名 | O-6-Amino-6-deoxy-L-glycero-D-galac |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Aminoglycoside antibiotic. Active against both prokaryotic and eukaryotic cells. Inhibits protein synthesis by binding to the 30S subunit and inhibiting the ribosomal translocation step of elongation. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >90 % |
| 计算分子量 | 527.52 |
| 分子式 | C20H37N3O13< |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| 参考文献 | Ganoza and Kiel (2001) A ribosomal ATPase is a target for hygromycin B inhibition on Escherichia coli ribosomes. Antimicrob.Agents Chemother. 45 2813. PMID: 11557474. Brodersenet al (2000) The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell 103 1143. PMID: 11163189. Blochlinger and Diggelmann (1984) Hygromycin B phosphotransferase as a selectable marker for DNA transfer experiments with higher eukaryotic cells. Mol.Cell.Biol. 4 2929. PMID: 6098829. |