| 货号 | 1416/10 |
| 别名 | Cephalotaxine 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methy |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of protein synthesis. Blocks elongation phase of translation by binding to the 60-S ribosome subunit. Antileukemic. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 545.63 |
| 分子式 | C29H39NO9 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| 参考文献 | Caiet al (2001) Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation. Leukemia 15 567. PMID: 11368358. Zhouet al (1995) Homoharringtonine: an effective new natural product in cancer chemotherapy. Bull.Cancer 82 987. PMID: 8745664. Fresnoet al (1977) Inhibition of translation in eukaryotic systems by harringtonine. Eur.J.Biochem. 72 323. PMID: 319998. |