| 货号 | 1087/10U |
| 别名 | ChTx |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Specific inhibitor of the big conductance Ca2+-activated K+channel. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4295.95 |
| 分子式 | C176H277N57O |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | XFTNVSCTTSKECWSVCQRLHNTSRGKCMN (Modifications: X-1 = Glp, Disulfide bridge between 7 - 28, 13 - 33,17 - 35, Ser-37 = C-terminal OH) |
| 参考文献 | Asanoet al (1993) Charybdotoxin-sensitive K+ channels regulate the myogenic tone in the resting state of arteries from spontaneously hypertensive rats. Br.J.Pharmacol. 108 214. PMID: 7679030. Gimenez-Gallegoet al (1988) Purification, sequence, and model structure of charybdotoxin, a potent selective inhibitor of calcium activated potassium channels. Proc.Natl.Acad.Sci.U.S.A. 85 3329. PMID: 2453055. Milleret al (1985) Charybdotoxin, a protein inhibitor of single Ca2+ activated K+ channels from mammalian skeletal muscle. Nature 313 316. PMID: 2578618. |