| 货号 | 1100/25 |
| 别名 | (S)-4-Ethyl-4-hydroxy-1H-pyrano-[3', |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Cytotoxic plant alkaloid with antitumor properties; prototypic DNA topoisomerase I inhibitor. Induces single strand DNA breaks and protein-DNA crosslinks. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 348.36 |
| 分子式 | C20H16N2O4 |
| 可溶性/溶解性 | Soluble to 5 mM in DMSO |
| 参考文献 | Pantaziset al (1993) Camptothecin derivatives induce regression of human ovarian carcinomas grown in nude mice and distinguish between non-tumorigenic and tumorigenic cells in vitro. Int.J.Cancer 53 863. PMID: 8449612. Liu (1989) DNA topoisomerase poisons as antitumour drugs. Annu.Rev.Biochem 58 351. PMID: 2549853. Hsianget al (1985) Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J.Biol.Chem. 260 14873. PMID: 2997227. Merck Index 121783. |