| 货号 | 5420/50 |
| 别名 | (3,5-Dibromo-4-hydroxyphenyl)(2-eth |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | TMEM16A/B calcium-activated chloride channel (CaCC) blocker. Inhibits ATP-induced mucin secretion and metacholine-induced airway smooth muscle contraction in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 424.08 |
| 分子式 | C17H12Br2O3< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Galloset al (2013) Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle. Am.J.Physiol.Lung Cell Mol.Physiol. 305 625. PMID: 23997176. Huanget al (2012) Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc.Natl.Acad.Sci.U.S.A. 109 16354. PMID: 22988107. |