| 货号 | 2503/10 |
| 别名 | [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofur |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
| 供应商 | Tocris |
| 生物活性 | Methiodide form of classical GABAA receptor antagonist (+)-bicuculline (Cat. No. 0130). More water-soluble and stable. Non-GABA receptor-mediated actions reported, including actions on calcium-dependent potassium channels. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 509.3 |
| 分子式 | C21H20INO6 |
| 可溶性/溶解性 | Soluble to 20 mM in water and to 50 mM in DMSO |
| 参考文献 | Chanet al (2006) Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia. Diabetes 55 1080. PMID: 16567532. Kurtet al (2006) Differential effects of iontophoretic in vivo application of the GABAA-antagonists bicuculline and gabazine in sensory cortex. Hear.Res. 212 224. PMID: 16442250. Seutin and Johnson (1999) Recent advances in the pharmacology of quaternary salts of bicuculline. TiPS 20 268. PMID: 10390643. Olsenet al (1976) Studies on the neuropharmacological activity of bicuculline and related compounds. Brain Res. 102 283. PMID: 1247886. |