| 货号 | 0247/50 |
| 别名 | 3-((R)-2-Carboxypiperazin-4-yl)-pro |
| 供应商 | Tocris |
| 生物活性 | Highly potent NMDA antagonist; more active isomer. Shows some selectivity for NR2A-containing receptors (Ki values are 0.041, 0.27, 0.63 and 1.99 μM for inhibition of NR2A-, NR2B-, NR2C- and NR2D-containing recombinant NMDA receptors respectively). (RS)-CPP (Cat. No. 0173) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 252.21 |
| 分子式 | C8H17N2O5P |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 126453-07-4 |
| 参考文献 | Fenget al (2004) Structure-activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid. Br.J.Pharmacol. 141 508. PMID: 14718249. Aebischeret al (1989) Synthesis and NMDA antagonistic properties of the enantiomers of 4-(3-phosphonopropyl)piperazine-2-carboxylic acid (CPP) and of the unsaturated analogue (E)-4-(3-phosphono-2-enyl)piperazine-2-carboxylic acid (CPP-ene). Helv.Chim.Acta 721043. |