Rhapontigenin
货号：
13293-25mg 基本售价：
17640.0 元 规格：
25 mg
产品信息
概述| 货号 | 13293-25mg |
| 描述 | Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens.1 At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC50 = 48 μM).2,3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Chun, Y.J.,Ryu, S.Y.,Jeong, T.C., et al. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin. Drug Metabolism and Disposition 29(4), 389-393 (2001).
2.Roupe, K.A.,Helms, G.L.,Halls, S.C., et al. Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: Applications to metabolism, pharmacokinetics and anti-cancer studies. Journal of Pharmacy & Pharmaceutical Sciences 8(3), 374-386 (2005).
3.Roberti, M.,Pizzirani, D.,Simoni, D., et al. Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. Journal of Medicinal Chemistry 46, 3546-3554 (2003).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 258.3 |
| 分子式 | C15H14O4 |
| CAS号 | 500-65-2 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
