货号 | 1546/50 |
别名 | (4S)-1,4-Dihydro-2,6-dimethyl-5-nit |
供应商 | Tocris |
生物活性 | L-type Ca2+-channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo. Enantiomer of (±)-Bay K 8644 (Cat. No. 1544). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 356.3 |
分子式 | C16H15F3N2O4 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
CAS号 | 98625-26-4 |
参考文献 | Ravens and Schopper (1990) Opposite cardiac actions of the enantiomers of Bay K 8644 at different membrane potentials in guinea-pig papillary muscles. Naunyn Schmiedebergs Arch.Pharmacol. 341 232. PMID: 1692975. O'Neill and Bolger (1988) Enantiomer selectivity and the development of tolerance to the behavioral effects of the calcium channel activator BAY K 8644. Brain Res.Bull. 21 865. PMID: 2465070. Franckowiaket al (1985) The optical isomers of the 1,4-dihydropyridine BAY K 8644 show opposite effects on Ca channels. Eur.J.Pharmacol. 114 223. PMID: 2412855. |