| 货号 | 0284/50 |
| 别名 | (1S,3R)-1-Aminocyclopentane-1,3-dic |
| 供应商 | Tocris |
| 生物活性 | Active isomer of (±)-trans-ACPD (Cat. No. 0187). Agonist at both group I and II mGlu receptors (EC50 values are 5, 15, 42 and 60 μM at mGluR2, mGluR5, mGluR1 and mGluR6 respectively). NPEC-caged-(1S,3R)-ACPD also available (Cat. No. 3331). (±)-trans-ACPD (Cat. No. 0187) and cis-ACPD (Cat. No. 0186) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 173.17 |
| 分子式 | C7H11NO4 |
| 可溶性/溶解性 | Soluble to 30 mM in water |
| CAS号 | 111900-32-4 |
| 参考文献 | Contiet al (2002) Synthesis and pharmacology of 3-hydroxy-Δ2-isoxazoline-cyclopentance analogues of glutamic acid. Farmaco 57 889. PMID: 12484537. Mistry and Challis (1996) Differences in agonist and antagonist activities for two indicies of metabotropic glutamate receptor-stimulated phosphoinositide turnover. Br.J.Pharmacol. 117 1735. PMID: 8732284. Knopfelet al (1995) Metabotropic glutamate receptors: novel targets for drug development. J.Med.Chem. 38 1417. PMID: 7738999. |