VU 0364739 hydrochloride (50 MG)
货号：
4171/50 基本售价：
14356.2 元 规格：
50 mg
产品信息
概述| 货号 | 4171/50 |
| 别名 | N-[2-[1-(3-Fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-2-naphthalenecarboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective phospholipase D2 (PLD2) inhibitor (IC50 = 20 nM); displays 75-fold selectivity against PLD1 (IC50 = 1500 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 482.98 |
| 分子式 | C26H27FN4O2< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Lavieriet al (2010) Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor. J.Med.Chem. 536709. |
