Resolvin D2 methyl ester
货号：
9001497-100ug 基本售价：
13832.0 元 规格：
100 ug
产品信息
概述| 货号 | 9001497-100ug |
| 描述 | Resolvin D2 (RvD2) (Item No. 10007279) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase.1 It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation.2,3 RvD2 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid. |
| 别名 | 7(S),16(R),17(S)-Resolvin D2 methyl ester;RvD2 methyl ester; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Seki, H.,Sasaki, T.,Ueda, T., et al. Resolvins as regulators of the immune system. ScientificWorldJournal 10, 818-831 (2010).
2.Serhan, C.N. Novel lipid mediators and resolution mechanisms in acute inflammation: To resolve or not? American Journal of Pathology 177(4), 1576-1591 (2011).
3.Spite, M.,Norling, L.V.,Summers, L., et al. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature 461(7268), 1287-1291 (2009).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥95% |
| 计算分子量 | 390.5 |
| 分子式 | C23H34O5 |
| CAS号 | 810668-53-2 |
| 稳定性 | ≥ 1 year |
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