ATB-343
货号：
13045-50mg 基本售价：
13720.0 元 规格：
50 mg
产品信息
概述| 货号 | 13045-50mg |
| 描述 | Hydrogen sulfide (H2S) is a naturally-occurring gasotransmitter with vasodilator and inflammatory modulating activity.1 Non-steroidal anti-inflammatory drugs (NSAIDs), such as indomethacin, diclofenac, and ibuprofen, are some of the most commonly used anti-inflammatory drugs available but exhibit significant side effects, particularly gastric damage, when used chronically. ATB-343 is a hybrid molecule of an H2S donor and the NSAID indomethacin. In rats, ATB-343 does not cause gastric damage or promote leukocyte adherence to vascular endothelium, effects which are observed with indomethacin treatment alone.2 These results indicate that H2S-releasing derivatives of NSAIDs may prove to be more effective anti-inflammatory agents than traditional NSAIDs alone. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Li, L., and Moore, P.K. Putative biological roles of hydrogen sulfide in health and disease: A breath of not so fresh air? Trends in Pharamacological Sciences 29(2), 84-90 (2007).
2.Wallace, J.L. Hydrogen sulfide-releasing anti-inflammatory drugs. Trends in Pharamacological Sciences 28(10), 501-505 (2007).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 566.1 |
| 分子式 | C28H20ClNO4S3 |
| CAS号 | 1000700-26-4 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
