Pyridomycin
货号：
17095-2.5mg 基本售价：
13608.0 元 规格：
2.5 mg
产品信息
概述| 货号 | 17095-2.5mg |
| 描述 | Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid.1 It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 µg/ml).2 |
| 别名 | Erizomycin;NSC 246134; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Huang, T.,Wang, Y.,Yin, J., et al. Identification and characterization of the pyridomycin biosynthetic gene cluster of Streptomyces pyridomyceticus NRRL B-2517. The Journal of Biological Chemisty 286(23), 20648-20657 (2011).
2.Hartkoorn, R.C.,Sala, C.,Neres, J., et al. Towards a new tuberculosis drug: Pyridomycin - nature’s isoniazid. EMBO Mol.Med. 4(10), 1032-1042 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 540.6 |
| 分子式 | C27H32N4O8 |
| CAS号 | 18791-21-4 |
| 稳定性 | ≥ 2 years |
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