3-hydroxy Palmitic Acid
货号：
19934-1g 基本售价：
13524.0 元 规格：
1 g
产品信息
概述| 货号 | 19934-1g |
| 描述 | 3-hydroxy Palmitic acid is a form of the 16:0 lipid palmitic acid (Item No. 10006627). The lipid A part of lipopolysaccharides contain various 3-hydroxy fatty acids, making oxylipins such as 3-hydroxy palmitic acid useful as chemical markers of endotoxins.1InR. solanacearum, 3-hydroxy palmitic acid is converted by an S-adenosyl methionine-dependent methyltransferase to 3-hydroxy palmitic acid methyl ester, which acts as a quorum sensing signal molecule for post-transcriptional modulation of genes involved in virulence.2 Long-chain 3-hydroxy fatty acids, such as 3-hydroxy palmitic acid, are also known to accumulate during long-chain 3-hydroxy-acyl-CoA dehydrogenase and mitochondrial trifunctional protein deficiencies.3 Such accumulation induces oxidative stress, leading to mitochondrial bioenergetics deregulation and eventual multi-organ dysfunction.3 |
| 别名 | β-hydroxy Hexadecanoic Acid;β-hydroxy Palmitic Acid;DL-3-hydroxy Palmitic Acid; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Uhlig, S.,Negård, M.,Heldal, K.K., et al. Profiling of 3-hydroxy fatty acids as environmental markers of endotoxin using liquid chromatography coupled to tandem mass spectrometry. J.Chromatogr.A. 1434, 119-236 (2016).
2.Shinohara, M.,Nakajima, N. and Uehara, Y. Purification and characterization of a novel esterase (β-hydroxypalmitate methyl ester hydrolase) and prevention of the expression of virulence by Ralstonia solanacearum. J.Appl.Microbiol. 103(1), 152-162 (2007).
3.Tonin, A.M.,Amaral, A.U.,Busanello, E.N., et al. Mitochondrial bioenergetics deregulation caused by long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies in rat brain: A possible role of mPTP opening as a pathomechanism in these disorders? Biochim Biophys.Acta. 1842(9), 1658-1667 (2014).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 272.4 |
| 分子式 | C16H32O3 |
| CAS号 | 2398-34-7 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
