ThioFluor 623
货号：
13083-50mg 基本售价：
13524.0 元 规格：
50 mg
产品信息
概述| 货号 | 13083-50mg |
| 描述 | The rapid, selective, and sensitive sensing of thiols is important in diverse areas of research. This thiofluor 623 responds upon exposure to thiols with an increase in fluorescence intensity of up to 120-fold.1 The response is selective for thiols and occurs in aqueous media.1 In the absence of thiols, the probe is essentially non-fluorescent; thiols cause cleavage of the probe, generating a fluorophore with an absorption maximum of 563 nm and emission at 623 nm.1 The fluorescence quantum yield of the cleaved product, generated in response to thiols, increases in more viscous media, suggesting ideal performance in biological systems and applicability to single-molecule or 2-photon sensing schemes. The thiofluor 623 is cell-permeable and reacts selectively with intracellular thiols.1 The pseudo-first order rate constant (kobs) depends on substrate (e.g., 2.1 x 10−3s−1 for cysteine, 2.0 x 10−5s−1 for human serum albumin).1 |
| 别名 | Fluorescent Thiol Probe; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bouffard, J.,Kim, Y.,Swager, T.M., et al. A highly selective fluorescent probe for thiol bioimaging. Organic Letters 10(1), 37-40 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 678.7 |
| 分子式 | C31H30N6O10S |
| CAS号 | 1004324-99-5 |
| 稳定性 | ≥ 2 years |
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