BS-181
货号：
17996-50mg 基本售价：
13482.0 元 规格：
50 mg
产品信息
概述| 货号 | 17996-50mg |
| 描述 | BS-181 is a Cdk7 inhibitor that blocks the activity of Cdk-activating kinase with an IC50 value of 21 nM.1 It inhibits Cdk2 at a concentration 35-fold higher than that of Cdk7.1 BS-181 has been shown to inhibit the phosphorylation of Cdk7 substrates, to promote cell cycle arrest and apoptosis, to inhibit the growth of cancer cell lines in vitro, and to inhibit the growth of MCF-7 human xenografts in nude mice.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ali, S.,Heathcote, D.A.,Kroll, S.H.B., et al. The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity. Cancer Res. 69(15), 6208-6215 (2009).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 417 |
| 分子式 | C22H32N6• HCl |
| CAS号 | 1397219-81-6 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
