UNC 1215 (50 MG)
货号：
4666/50 基本售价：
13463.9 元 规格：
50 mg
产品信息
概述| 货号 | 4666/50 |
| 别名 | 2-Phenylamino-1,4-[4-(pyrrolidinyl)piperidinyl)benzamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent inhibitor of L3MBTL3 methyllysine (Kme) reader domain (IC50 = 40 nM; Kd = 120 nM). Displays >100-fold selectivity over a panel of histone methyltransferases, kinases, ion channels and 7-TM receptors. Disrupts subnuclear localization and foci formation of fluorescently-labeled L3MBTL3 in HEK293 cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 529.72 |
| 分子式 | C32H43N5O2 |
| 可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in 2eq.HCl |
| 参考文献 | Jameset al (2013) Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat.Chem.Biol. [Epub ahead of print]. PMID: 23292653. |
