GPP 78 hydrochloride (50 MG)
货号：
4835/50 基本售价：
13463.9 元 规格：
50 mg
产品信息
概述| 货号 | 4835/50 |
| 别名 | N-[1,1'-Biphenyl]-2-yl-4-(3-pyridinyl)-1H,1,2,3-triazole-1-octanamide hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Inhibitor of nicotinamide phosphoribosyltransferase (NAMPT); potently depletes NAD levels and exhibits cytotoxicity in vitro(IC50 values are 3.0 and 3.8 nM respectively). Also shown to induce autophagy in neuroblastoma cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 476.01 |
| 分子式 | C27H29N5O.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Colombanoet al (2010) A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry. J.Med.Chem. 53 616. PMID: 19961183. |
