| 货号 | 4478/50 |
| 别名 | 4-[[3,5-Bis(trifluoromethyl)phenyl] |
| 供应商 | Tocris |
| 生物活性 | GPBA receptor agonist. Upregulates GLP-1 secretion from intestinal cultures. Increases MQAE-fluorescence suggesting a decrease in intracellular chloride concentration in gallbladder epithelial cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 484.37 |
| 分子式 | C23H15F7N2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Parkeret al (2012) Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion. Br.J.Pharmacol. 165 414. PMID: 21718300. Keitelet al (2009) The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders. Hepatology 50 861. PMID: 19582812. |