| 货号 | 4800/50 |
| 别名 | α-[2-[4-(3,4-Dichlorophenyl)-2-thiaz |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of eIF4E:eIF4G interaction; prevents eIF4E binding to eIF4G. Binds eIF4E and inhibits cap-dependent translation but not initiation factor-independent translation. Exhibits activity against Jurkat and A549 cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 451.28 |
| 分子式 | C18H12Cl2N4< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Gkogkaset al (2013) Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature 493 371. PMID: 23172145. Moerkeet al (2007) Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G. Cell 128 257. PMID: 17254965. |