| 货号 | 4953/50 |
| 别名 | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5 |
| 供应商 | Tocris |
| 生物活性 | Hydrochloride salt of CHIR 99021 (Cat. No. 4423), a highly selective GSK-3 inhibitor. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 574.72 |
| 分子式 | C22H18Cl2N8< |
| 可溶性/溶解性 | Soluble to 25 mM in water and to 50 mM in DMSO |
| 参考文献 | Yeet al (2012) Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embyronic stem cells from refractory mouse strains. PLoS One 7 e35892. PMID: 22540008. Panet al (2011) AKT kinase activity is required for lithium to modulate mood-related behaviors in mice. Neuropsychopharmacology 36 1397. PMID: 21389981. Ringet al (2003) Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52 588. PMID: 12606497. |