TC-SP 14 (50 MG)
货号：
4363/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 4363/50 |
| 别名 | 1-[[3-Fluoro-4-[5-[(2-fluorophenyl)methyl]-2-benzothiazolyl]phenyl]methyl]-3-azetidinecarboxylic acid |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective S1P1 agonist (EC50 values are 0.042 and 3.47 μM for human S1P1 and S1P3 respectively). Attenuates immune response to antigen challenge and reduces circulating blood lymphocyte counts in a rodent model of delayed-type hypersensitivity. Orally bioavailable. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 450.5 |
| 分子式 | C25H20F2N2 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO with gentle warming |
| 参考文献 | Lanmanet al (2011) Discovery of a potent, S1P3-sparing benzothiazole agonist of sphingosine-1-phosphate receptor 1 (S1P1). ACS Med.Chem.Lett. 2102. |
