TC-N 22A (50 MG)
货号：
4370/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 4370/50 |
| 别名 | 4,5,6,8-Tetrahydro-N-2-pyridinylpyrazolo[3',4':6,7]cyclohepta[1,2]thiazol-2-amine |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective mGlu4 receptor positive allosteric modulator (EC50 = 9 nM in human mGlu4-expressing BHK cells). Selective for mGlu4 over mGlu1, mGlu2, mGlu3, mGlu5 and mGlu7 receptors (EC50 values are > 10 μM). Brain penetrant. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 283.35 |
| 分子式 | C14H13N5S |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Honget al (2011) Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators. J.Med.Chem. 54 5070. PMID: 21688779. |
