TC-G 1006 (50 MG)
货号：
4747/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 4747/50 |
| 别名 | 4-Methoxy-N-[[[2-trifluoromethyl)[1,1'-biphenyl]-4-yl]amino]carbonyl]-3-pyridinecarboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective sphingosine-1-phosphate receptor 1 (S1P1) agonist (EC50 = 35 nM), displays >100-fold selectivity against receptor subtypes S1P2-5. Induces a dose-dependent reduction in circulating blood lymphocyte counts in rodent models. Orally bioavailable. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 415.37 |
| 分子式 | C21H16F3N3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Penningtonet al (2011) 4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1. ACS Med.Chem.Lett. 2 752. PMID: 24900263. |
