TC 1 (50 MG)
货号：
2669/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 2669/50 |
| 别名 | (N-(3'-Fluorophenyl)ethyl-4-azahexacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecan-3-ol |
性能| 供应商 | Tocris |
| 生物活性 | High affinity σ1 receptor ligand that displays selectivity over σ2 receptors (Ki values are 10 and 370 nM respectively). Exhibits low affinity for dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters (Ki > 10 μM) and low affinity for dopamine D2 receptors (Ki = 1226 nM). Attenuates cocaine-induced locomotor activity in mice. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 297.37 |
| 分子式 | C19H20FNO |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO with gentle warming and to 50 mM in ethanol with gentle warming |
| 参考文献 | Liuet al (2007) Trishomocubanes: novel σ ligands modulate cocaine-induced behavioural effects. Eur.J.Pharmacol. 555 37. PMID: 17113074. |
