SU 16f (50 MG)
货号：
3304/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 3304/50 |
| 别名 | 5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective platelet-derived growth factor receptor β(PDGFRβ) inhibitor (IC50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro(IC50 = 0.11 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 386.44 |
| 分子式 | C24H22N2O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 251356-45-3 |
| 参考文献 | Sunet al (1999) Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases. J.Med.Chem. 42 5120. PMID: 10602697. |
