PYZD 4409 (50 MG)
货号：
4994/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 4994/50 |
| 别名 | 1-(3-Chloro-4-fluorophenyl)-4-[(5-nitro-2-furanyl)methylene]-3,5-pyrazolidinedione |
性能| 供应商 | Tocris |
| 生物活性 | Ubiquitin-activating enzyme (E1) inhibitor. Blocks degradation of p53 and cyclin D3. Inhibits NF-κB activation and induces cell death associated with ER stress. Displays antitumor effects in a mouse model of leukemia. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 351.67 |
| 分子式 | C14H7ClFN3O5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Xuet al (2010) The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma. Blood 115 2251. PMID: 20075161. |
