| 货号 | 2274/50 |
| 别名 | (2R*,4S*)-4-(3-Phosphonopropyl)-2-p |
| 供应商 | Tocris |
| 生物活性 | Competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors (Ki values are 0.13, 0.47, 1.10 and 3.86 μM for NR2A, NR2B, NR2C and NR2D subunits respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 251.22 |
| 分子式 | C9H18NO5P |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| 参考文献 | Fenget al (2005) The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacology 48 354. PMID: 15721167. Kinarskyet al (2005) Identification of subunit- and antagonist-specific amino acid residues in the N-methyl-D-aspartate receptor glutamate-binding pocket. J.Pharmacol.Exp.Ther. 313 1066. PMID: 15743930. Benveniste and Mayer (1992) Effect of extracellular pH on the potency of N-methyl-D-aspartic acid receptor competitive antagonists. Mol.Pharmacol. 42 679. PMID: 1435743. |