货号 | 3307/50 |
别名 | N-Phenyl-4-(3-quinolinylmethyl)-1-p |
供应商 | Tocris |
生物活性 | Irreversible fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 345.44 |
分子式 | C22H23N3O |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
CAS号 | 959151-50-9 |
参考文献 | Mileniet al (2008) Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc.Natl.Acad.Sci.USA 10512820. Ahnet al (2007) Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 46 13019. PMID: 17949010. |