| 货号 | 3239/50 |
| 别名 | 3,4-Dihydro-6-[[4-[[[3-(methylsulfo |
| 供应商 | Tocris |
| 生物活性 | Potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM). Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 491.49 |
| 分子式 | C22H20F3N5O3S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 869288-64-2 |
| 参考文献 | Kostourouet al (2013) FAK-heterozygous mice display enhanced tumour angiogenesis. Nat.Commun. 5 2020. PMID: 23799510. Slack-Daviset al (2007) Cellular characterization of a novel focal adhesion kinase inhibitor. J.Biol.Chem. 282 14845. PMID: 17395594. . |