NTNCB hydrochloride (50 MG)
货号:
2155/50 基本售价:
12274.1 元 规格:
50 mg
产品信息
概述货号 | 2155/50 |
别名 | 2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride |
性能供应商 | Tocris |
生物活性 | Selective, non-peptide competitive NPY Y5 antagonist. Ki values are 8.0 and 16032 nM at human recombinant Y5 and Y1 receptors respectively. Potently antagonizes NPY inhibition of forskolin-stimulated cAMP. Displays some affinity for cloned human D2andα2C receptors (Ki values are 63 and 100 nM respectively). |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 508.07 |
分子式 | C25H33N3O4S.HCl |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 486453-65-0 |
参考文献 | Islamet al (2002) Discovery of potent and selective small molecule NPY Y5 receptor antagonists. Bioorg.Med.Chem.Lett. 12 1767. PMID: 12067557. |