| 货号 | 4866/50 |
| 别名 | N-[3-[4-(4-Methoxyphenyl)-1-piperaz |
| 供应商 | Tocris |
| 生物活性 | Selectiveκ opioid receptor (KOP) antagonist (IC50 = 120 nM in a β-arrestin assay); displays >267-fold selectivity over μandδ opioid receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 488.58 |
| 分子式 | C27H32N6O3 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Frankowskiet al (2012) Discovery of small molecule kappa opioid receptor agonist and antagonist chemotypes through a HTS and hit refinement strategy. ACS Chem.Neurosci. 3 221. PMID: 22737280. Hedricket al (2011) Antagonist for the kappa opioid receptor. Probe Reports from the NIH Molecular Libraries Pro. PMID: 22091479. |