| 货号 | 2198/50 |
| 别名 | (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2 |
| 供应商 | Tocris |
| 生物活性 | Ca2+ channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50 values of 2.7 μM and 18.6 μM for T-type and L-type channels respectively. Antihypertensive agent. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 568.56 |
| 分子式 | C29H38FN3O3.2HCl |
| 可溶性/溶解性 | Soluble to 50 mM in water and to 100 mM in DMSO |
| CAS号 | 116644-53-2 |
| 参考文献 | Mehrkeet al (1994) The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L-type Ca++ channels. J.Pharmacol.Exp.Ther. 271 1483. PMID: 7996461. Veniantet al (1991) Hemodynamic profile of Ro 40-5967 in conscious rats: comparison with diltiazem, verapamil, and amlodipine. J.Cardiovasc.Pharmacol. 18 (Suppl 10 ) S55. PMID: 1725005. Osterrieder and Holck(1989)In vitro pharmacologic profile of Ro 40-5967, a novel Ca2+ channel blocker with potent vasodilator but weak inotropic action. J.Cardiovasc.Pharmacol. 13 754. PMID: 2472524. |