| 货号 | 4081/50 |
| 别名 | 1-[(2-Chloro-3,4-dimethoxyphenyl)me |
| 供应商 | Tocris |
| 生物活性 | Selective 5-HT2B receptor antagonist (pKi = 9.3). More than 100-fold selective over 5-HT2A and 5-HT2C. Attenuates amphetamine-induced locomotion in the rat. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 407.33 |
| 分子式 | C21H23ClN2O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Auclairet al (2010) The central serotonin2B receptor: a new pharmacological target to modulate the mesoaccumbens dopaminergic pathway activity. J.Neurochem. 114 1323. PMID: 20534001. Audiaet al (1996) Potent, selective tetrahydro-β-carboline antagonists of the serotonin 2B (5-HT2B) contractile receptor in the rat stomach fundus. J.Med.Chem. 39 2773. PMID: 8709108. |