IWP L6 (50 MG)
货号：
4992/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 4992/50 |
| 别名 | N-(5-Phenyl-2-pyridinyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]acetamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM). Shown to inhibit Wnt-dependent processes such as tailfin regeneration and posterior axis formation in zebrafish; also reduces branching morphogenesis in cultured mouse embryonic kidneys. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 472.58 |
| 分子式 | C25H20N4O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Wanget al (2013) The development of highly potent inhibitors for Porcupine. J.Med.Chem. 56 2700. PMID: 23477365. |
