| 货号 | 1066/25 |
| 别名 | 1-Deoxy-1-[6-[[(3-iodophenyl)methyl |
| 供应商 | Tocris |
| 生物活性 | Potent and selective A3 adenosine receptor agonist (Ki values are 1.1, 54 and 56 nM for A3, A1 and A2A receptors respectively). Cardioprotective, reduces infarct size upon reperfusion in rats. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >97 % |
| 计算分子量 | 510.29 |
| 分子式 | C18H19IN6O4 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| CAS号 | 152918-18-8 |
| 参考文献 | Parket al (2006) N6-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide confers cardioprotection at reperfusion by inhibiting mitochondrial permeability transition pore opening via glycogen synthase kinase 3β. J.Pharmacol.Exp.Ther. 318 124. PMID: 16611852. Klotz (2000) Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch.Pharmacol. 362 382. PMID: 11111832. Gallo-Rodriguezet al (1994) Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists. J.Med.Chem. 37 636. PMID: 8126704. |