| 货号 | 3099/50 |
| 别名 | 4-(8-Chloro-2-methyl-11H-imidazo[1, |
| 供应商 | Tocris |
| 生物活性 | Non-competitive AMPA receptor antagonist (IC50 = 2.5 μM). Displays broad spectrum anticonvulsive activity and neuroprotective effects in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 395.71 |
| 分子式 | C18H15ClN4.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 220445-20-5 |
| 参考文献 | Bibbianiet al (2005) Combined blockade of AMPA and NMDA glutamate receptors reduces levodopa-induced motor complications in animal models of PD. Exp.Neurol. 196 422. PMID: 16203001. Solyo (2001) Research on new AMPA antagonists of 2,3-benzodiazepine type. Pharmazie 25 (Suppl. 1) S62. Abrahamet al (2000) New non competitive AMPA antagonists. Bioorg.Med.Chem. 8 2127. PMID: 11003158. |