| 货号 | 1246/50 |
| 别名 | 3-[[(3,4-Dichlorophenyl)methyl]amin |
| 供应商 | Tocris |
| 生物活性 | Potent, selective GABAB receptor antagonist (IC50 = 85 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 384.24 |
| 分子式 | C15H24Cl2NO4P |
| 可溶性/溶解性 | Soluble to 10 mM in water with sonication and to 100 mM in 1eq. NaOH |
| CAS号 | 139667-74-6 |
| 参考文献 | Bonannoet al (1998) GABAB receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord. Eur.J.Pharmacol. 362 143. PMID: 9874164. Libriet al (1998) Blockade of GABAB receptors facilitates muscarinic agonist-induced epileptiform activity in immature rat piriform cortex in vitro. Naunyn Schmiedebergs Arch.Pharmacol. 358 168. PMID: 9750001. Froestlet al (1996) Potent, orally active GABAB receptor antagonists. Pharmacol.Rev.Comm. 8127. Lanzaet al (1993) CGP 52432: a novel potent and selective GABAB autoreceptor antagonist in rat cerebral cortex. Eur.J.Pharmacol. 237 191. PMID: 8103461. |