货号 | 1469/50 |
别名 | (E)-(±)-2-Amino-4-methyl-5-phosphono |
供应商 | Tocris |
生物活性 | Potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). Anticonvulsive following oral administration in vivo. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 209.14 |
分子式 | C6H12NO5P |
CAS号 | 127910-31-0 |
参考文献 | Loscher and Honack (1991) Anticonvulsant and behavioural effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine. J.Pharmacol.Exp.Ther. 256 432. PMID: 1671593. Fagget al (1990) CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-asparate receptor antagonists with oral activity. Br.J.Pharmacol. 99 791. PMID: 1972895. Pozzaet al (1990) Electrophysiological characterization of a novel potent and orally active NMDA receptor antagonist: CGP 37849 and its ethylester CGP 39551. Eur.J.Pharmacol. 182 91. PMID: 1976098. |