货号 | 3800/50 |
别名 | 4-[6-[(2-Methoxyethoxy)methoxy]-7-t |
供应商 | Tocris |
生物活性 | Selective RARβγ antagonist (KD values are 110, 306 and > 1000 nM for RARγ, RARβ and RARα respectively). Blocks retinoic acid-induced apoptosis ex vivo. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 486.6 |
分子式 | C31H34O5 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 170355-78-9 |
参考文献 | Kimet al (2000) The role of specific retinoid receptors in sebocyte growth and differentiation in culture. J.Invest.Dermatol. 114 349. PMID: 10651997. Meisteret al (1998) Antiproliferative activity and apoptosis induced by retinoic acid receptor-gamma selectivity binding retinoids in neuroblastoma. Anticancer Res. 18 1777. PMID: 9673404. Szondyet al (1997) Induction of apoptosis by retinoids and retinoic acid receptor γ-selective compounds in mouse thymocytes through a novel apoptosis pathway. Mol.Pharmacol. 51 972. PMID: 9187263. |